GenomeView

GenomeView visualizes and edits large-scale genomic data to enable interactive exploration, comparative analysis, and refinement of aligned short-read mappings and annotations.

Key Features:

• Interactive Visualization: Offers dynamic browsing of aligned short-read data with semantic zooming from whole-genome views to individual nucleotides.
• Comprehensive Data Handling: Handles datasets comprising tens of aligned genomes, thousands of annotation features, and millions of mapped short reads for viewing and editing.
• Whole Genome Alignments: Visualizes whole-genome alignments relative to a reference sequence to support comparative genomics across dozens of genomes.
• Support for Multiple Formats and Plugins: Supports standard genomic file formats and a plugin system for integrating additional functionalities.

Scientific Applications:

• Comparative Genomics: Enables visualization and comparison of whole-genome alignments and variation across multiple genomes.
• Evolutionary Studies: Facilitates identification of conserved and divergent regions across aligned genomes.
• Functional Genomics Analyses: Supports examination of mapped short reads and annotations to assess gene models and functional elements.
• Genome Annotation and Curation: Provides interactive editing features to support annotation projects and refinement of genomic data.

Methodology:

Implements dynamic navigation and semantic zooming and an architecture for efficient management and rendering of large volumes of genomic information.