Genomics Virtual Lab

Genomics Virtual Lab enables high-throughput genomics analysis by integrating bioinformatics tools, large reference datasets, reproducible workflow platforms, and scalable cloud-based compute clusters.


Key Features:

  • Comprehensive Toolset: Includes a wide range of analysis and visualization bioinformatics tools integrated with user and large reference datasets.
  • Workflow Platforms: Supports reproducible and portable analyses via Galaxy, RStudio, IPython Notebook, and command-line environments.
  • Scalable Resources: Provides scalable computational resources with the ability to dynamically adjust compute clusters.
  • Cloud-Based Infrastructure: Implemented as a middleware layer of machine images, cloud management tools, and online services to enable construction of custom-sized compute clusters.
  • Flexibility in Compute and Data: Allows modification of compute nodes and data resources to meet analysis requirements.

Scientific Applications:

  • High-throughput genomics analysis: Supports compute-intensive processing and transformation of large genomic datasets.
  • Reproducible workflows: Enables reproducible execution of analysis pipelines and workflows for genomics research.
  • Large-reference-dataset analyses: Facilitates analyses that integrate substantial reference datasets alongside user data.

Methodology:

Implements cloud-agnostic middleware composed of machine images, cloud management tools, and online services to build and dynamically scale custom compute clusters across OpenStack-based Australian Research Cloud and Amazon Web Services.

Topics

Details

Tool Type:
workflow
Operating Systems:
Linux, Windows, Mac
Added:
10/2/2016
Last Updated:
1/11/2019

Operations

Publications

Afgan E, Sloggett C, Goonasekera N, Makunin I, Benson D, Crowe M, Gladman S, Kowsar Y, Pheasant M, Horst R, Lonie A. Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud. PLOS ONE. 2015;10(10):e0140829. doi:10.1371/journal.pone.0140829. PMID:26501966. PMCID:PMC4621043.

Documentation