GenoVault

GenoVault provides scalable, secure object-based cloud storage and controlled access for Next Generation Sequencing (NGS) data to support genomics research.


Key Features:

  • Object-Based Storage: Employs object-based storage across distributed nodes for efficient storage and rapid retrieval of large NGS datasets.
  • Scalability: Supports vertical and horizontal scaling via OpenStack cloud capabilities to accommodate growing data volumes without compromising performance.
  • Security and Access Control: Implements container-level access control with options for public or private data accessibility and uses Secure File Transfer Protocol (SFTP) for data upload and download.
  • Data Integrity and Authentication: Verifies data integrity and authenticity before sharing and enforces user-defined permissions for data access.
  • Comprehensive Data Support: Stores NGS file formats including raw reads (fastq), alignments (bam, sam, bed), and variant calls (vcf) within individual containers.
  • OpenStack Private Cloud Infrastructure: Built on an OpenStack-based private cloud to provide robust, scalable storage tailored to genomics research.

Scientific Applications:

  • Centralized NGS Repository: Acts as a centralized repository for research labs generating large volumes of unpublished NGS data.
  • Collaborative Data Sharing: Supports intra-organizational collaboration and controlled data sharing among partnering institutions.
  • Large-Scale Genomic Studies: Facilitates storage management for genomic studies that require extensive data analysis and long-term storage of large datasets.

Methodology:

Uses object-based storage and SFTP transfers, verifies data integrity and authenticity before sharing, and is implemented on OpenStack services including Keystone (authentication), Cinder (block storage), Neutron (networking), and Nova (compute).

Topics

Details

Added:
11/28/2021
Last Updated:
11/28/2021

Operations

Publications

Jain S, Saxena A, Hesarur S, Bhadhadhara K, Bharti N, Kasibhatla SM, Sonavane U, Joshi R. GenoVault: a cloud based genomics repository. BioData Mining. 2021;14(1). doi:10.1186/s13040-021-00268-5. PMID:34325724. PMCID:PMC8319889.

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