GEOSS

GEOSS manages and analyzes Affymetrix GeneChip microarray data to provide archival storage, controlled access, and construction of tree-structured analysis workflows for gene expression studies.

Key Features:

• Relational Database System: Uses a PostgreSQL relational database for storage and retrieval of microarray experiment metadata and expression data.
• Multiuser Archive: Provides multiuser archival storage and documentation for Affymetrix GeneChip experiments and associated analysis outputs.
• User Management and Security: Implements advanced security and access-control with customizable privileges for users, groups, and external collaborators and management of array data and analysis output files.
• Analysis Trees: Represents and constructs tree-structured analysis workflows and flow charts of analysis routines to support complex data-processing sequences.
• Affymetrix GeneChip Data Analysis: Supports analytical routines and statistical processing specifically for Affymetrix GeneChip microarray expression data.

Scientific Applications:

• Microarray Data Archiving: Archival storage and structured documentation of Affymetrix GeneChip experiments to support reproducible gene expression studies.
• Gene Expression Analysis: Construction and execution of complex analysis workflows and statistical analyses on Affymetrix GeneChip expression datasets.
• Institutional Data Management: Management of large multiuser microarray datasets with customizable access controls for laboratory and institutional bioinformatics operations.

Methodology:

Integrates PostgreSQL relational database management with analysis tools and employs Analysis Trees to construct tree-structured analytical workflows for storage, retrieval, and statistical analysis of Affymetrix GeneChip data.