GEPIA3

GEPIA3 provides pan-cancer analysis of gene expression data with enhanced drug sensitivity and interaction network analysis capabilities.

Key Features:

• Pan-cancer gene expression analysis: Analyzes gene and protein interactions across various cancer types.
• Drug sensitivity analysis: Investigates treatment sensitivity using real-world patient data and cell line screens for over 1000 therapeutic agents.
• RNA alteration integration: Integrates RNA alterations derived from the pan-cancer analysis of whole genomes project.
• Interaction network analysis: Provides comprehensive analysis of gene/protein interaction networks.

Scientific Applications:

• Gene regulation exploration: Enables in-depth exploration of gene regulation mechanisms in cancer.
• Cancer phenotype analysis: Supports investigation of cancer phenotypes through integrated multi-omics data.
• Biomarker identification: Facilitates identification of novel biomarkers for cancer diagnosis and prognosis.
• Therapeutic target discovery: Supports identification of therapeutic targets through drug sensitivity and network analysis.
• Precision therapeutics research: Aids discovery of gene-based precision therapeutics by deconvoluting complex regulatory relationships.

Methodology:

GEPIA3 analyzes gene/protein interactions across cancer types, integrates real-world patient data and cell line screens for drug sensitivity profiling, and incorporates RNA alterations from the pan-cancer analysis of whole genomes project.