GETdb

GETdb integrates and standardizes genetic and evolutionary features of drug targets from multiple databases and incorporates an allosteric protein prediction model to facilitate drug target identification.

Key Features:

• Multi-database integration: GETdb integrates and standardizes data from dozens of commonly used drug and target databases.
• Genetic and evolutionary information: GETdb includes genetic and evolutionary information of targets to facilitate identification of approved drug targets.
• Allosteric protein prediction model: GETdb features an effective allosteric protein prediction model to identify potential allosteric protein targets.
• Comprehensive target and drug coverage: GETdb contains approximately 4000 targets and over 29,000 drugs.

Scientific Applications:

• Drug target identification: GETdb facilitates effective and accurate identification of drug targets by providing evolutionary and genetic information of genes.
• Novel target development: GETdb supports the development of novel targets through integrated genetic, evolutionary, and allosteric protein data.

Methodology:

GETdb constructs a comprehensive drug target database by integrating and standardizing data from dozens of commonly used drug and target databases, and incorporates an allosteric protein prediction model.