getwigdata

getwigdata computes average values for specified genomic coordinates from WIG (Wiggle) format files to quantify coverage or signal intensity arising from next-generation DNA sequencing data.


Key Features:

  • Data handling and computation: Processes WIG (Wiggle) files to compute average values across specified genomic coordinates.
  • Integration with Galaxy Project: Operates within the Galaxy computational framework to enable reproducible execution of analyses.

Scientific Applications:

  • Biomedical research: Supports gene expression analysis, epigenetic studies, and comparative genomics by providing averaged coverage or signal intensity metrics.
  • Data-intensive studies: Facilitates processing of large-scale datasets generated by next-generation DNA sequencing to extract genomic signal summaries.

Methodology:

Processes WIG (Wiggle) format files representing continuous-valued genomic tracks (coverage or signal intensity) and computes average values across specified genomic coordinates while leveraging the Galaxy project computational framework.

Topics

Collections

Details

Maturity:
Mature
Tool Type:
web application
Operating Systems:
Linux, Windows, Mac
Added:
12/19/2016
Last Updated:
11/25/2024

Operations

Data Inputs & Outputs

Sequence composition calculation

Inputs

Outputs

Publications

Afgan E, Baker D, van den Beek M, Blankenberg D, Bouvier D, Čech M, Chilton J, Clements D, Coraor N, Eberhard C, Grüning B, Guerler A, Hillman-Jackson J, Von Kuster G, Rasche E, Soranzo N, Turaga N, Taylor J, Nekrutenko A, Goecks J. The Galaxy platform for accessible, reproducible and collaborative biomedical analyses: 2016 update. Nucleic Acids Research. 2016;44(W1):W3-W10. doi:10.1093/nar/gkw343. PMID:27137889. PMCID:PMC4987906.

Mareuil F, Doppelt-Azeroual O, Ménager H. A public Galaxy platform at Pasteur used as an execution engine for web services. Unknown Journal. 2017. doi:10.7490/f1000research.1114334.1.

Documentation

Links