gganatogram

gganatogram visualizes anatomical structures (anatograms) by mapping data-frame-specified tissue values onto species-specific diagrams using ggplot2 and anatograms from the Expression Atlas to support tissue-level data interpretation.

Key Features:

• Modular visualization: Generates customizable anatograms from a tabular data frame and supports visualization of datasets such as gene expression, pharmacokinetics, and bacterial load.
• Graphics backend and data sources: Integrates ggplot2's graphical grammar with publicly available anatograms sourced from the Expression Atlas.
• Species coverage: Provides highly annotated anatomical structures for male and female humans and mice plus a cell anatogram, and less-detailed anatograms for 24 additional animal and plant species.
• Data-driven customization and reproducibility: Allows specification of tissues, groupings, colors, and values within the data frame to produce reproducible visual outputs.

Scientific Applications:

• Genomics: Visualize tissue-specific gene expression patterns across annotated anatomical structures.
• Pharmacology: Represent pharmacokinetic and tissue-distribution data on anatomical diagrams.
• Microbiology: Map bacterial load or other microbial measures across tissues.
• Comparative anatomy: Support comparative studies by providing anatograms across multiple species including human, mouse, and 24 additional species.
• Data interpretation and hypothesis generation: Aid interpretation of tissue-level datasets and support hypothesis generation and testing.

Methodology:

Combines the graphical grammar of ggplot2 with anatomical data from the Expression Atlas and maps data-frame-specified values onto species-specific annotated anatograms.