ggVolcanoR

ggVolcanoR generates customizable visualizations of differential expression datasets to support interpretation in transcriptomic and proteomic analyses.


Key Features:

  • Customizable Plot Generation: Supports creation of volcano plots, correlation plots, upset plots, and heatmaps for analysis of dysregulated expression data.
  • Comparative Analysis Capabilities: Provides enhanced options for analyzing and comparing dysregulated genes or proteins across multiple datasets with customization aimed at publication-quality figures.
  • Data Export Functionality: Exports customized lists of filtered dysregulated expression data suitable for downstream pathway analysis.

Scientific Applications:

  • Transcriptomic Analysis: Visualization and interpretation of differential gene expression in transcriptomic studies.
  • Proteomic Analysis: Visualization and interpretation of differential protein expression in proteomic studies.
  • Pathway Analysis and Biomarker Discovery: Generation of filtered gene/protein lists and plots to support pathway analysis and biomarker identification.
  • Comparative Studies: Comparative analysis of dysregulated genes or proteins across multiple experimental conditions or datasets.

Methodology:

Implemented in R using the Shiny framework for interactive data visualization of differential expression results.

Topics

Details

Cost:
Free of charge
Tool Type:
library, web application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
R
Added:
5/7/2022
Last Updated:
5/7/2022

Operations

Publications

Mullan KA, Bramberger LM, Munday PR, Goncalves G, Revote J, Mifsud NA, Illing PT, Anderson A, Kwan P, Purcell AW, Li C. ggVolcanoR: A Shiny app for customizable visualization of differential expression datasets. Computational and Structural Biotechnology Journal. 2021;19:5735-5740. doi:10.1016/j.csbj.2021.10.020. PMID:34745458. PMCID:PMC8551465.

Links