ggVolcanoR
ggVolcanoR generates customizable visualizations of differential expression datasets to support interpretation in transcriptomic and proteomic analyses.
Key Features:
- Customizable Plot Generation: Supports creation of volcano plots, correlation plots, upset plots, and heatmaps for analysis of dysregulated expression data.
- Comparative Analysis Capabilities: Provides enhanced options for analyzing and comparing dysregulated genes or proteins across multiple datasets with customization aimed at publication-quality figures.
- Data Export Functionality: Exports customized lists of filtered dysregulated expression data suitable for downstream pathway analysis.
Scientific Applications:
- Transcriptomic Analysis: Visualization and interpretation of differential gene expression in transcriptomic studies.
- Proteomic Analysis: Visualization and interpretation of differential protein expression in proteomic studies.
- Pathway Analysis and Biomarker Discovery: Generation of filtered gene/protein lists and plots to support pathway analysis and biomarker identification.
- Comparative Studies: Comparative analysis of dysregulated genes or proteins across multiple experimental conditions or datasets.
Methodology:
Implemented in R using the Shiny framework for interactive data visualization of differential expression results.
Topics
Details
- Cost:
- Free of charge
- Tool Type:
- library, web application
- Operating Systems:
- Mac, Linux, Windows
- Programming Languages:
- R
- Added:
- 5/7/2022
- Last Updated:
- 5/7/2022
Operations
Publications
Mullan KA, Bramberger LM, Munday PR, Goncalves G, Revote J, Mifsud NA, Illing PT, Anderson A, Kwan P, Purcell AW, Li C. ggVolcanoR: A Shiny app for customizable visualization of differential expression datasets. Computational and Structural Biotechnology Journal. 2021;19:5735-5740. doi:10.1016/j.csbj.2021.10.020. PMID:34745458. PMCID:PMC8551465.
Links
Repository
https://github.com/KerryAM-R/ggVolcanoR