Giotto Suite

Giotto Suite provides a multiscale and technology-agnostic ecosystem for spatial multiomics data analysis, integration, and visualization.

Key Features:

• Technology-agnostic data framework: Represents and integrates spatial omics data independently of the underlying technology platform.
• Multi-information integration: Integrates molecular, morphology, spatial, and annotated feature information into unified analyses.
• Scalable and extensible architecture: Provides modular packages with end-to-end solutions that scale to large and diverse spatial datasets.
• Interoperable interfaces: Bridges genomics and spatial data science in R through interoperable data structures and interfaces for custom pipeline development.
• Multiscale analysis: Supports analysis across multiple spatial scales for spatial multiomic data.

Scientific Applications:

• Spatial multiomics data analysis: Processes and analyzes diverse spatial datasets from state-of-the-art spatial technologies.
• Spatial data integration: Harmonizes and integrates diverse spatial datasets across molecular, morphological, and spatial dimensions.
• Spatial omics visualization: Creates visual representations of integrated spatial multiomics data.
• Custom pipeline development: Enables independent developers to create custom-engineered spatial analysis pipelines.

Methodology:

Giotto Suite is implemented as a suite of modular packages in R, centered around an innovative data framework that represents spatial omics data in a technology-agnostic manner and builds upon interoperable interfaces and data structures bridging genomics and spatial data science.