GlycoGlyph

GlycoGlyph provides visualization and nomenclature conversion of glycan structures to support standardized representation and data exchange in glycomics.


Key Features:

  • Modified IUPAC-condensed support: Implements the modified IUPAC-condensed nomenclature system employed by the Consortium for Functional Glycomics for standardized naming.
  • Glycan structure construction and parsing: Constructs and parses graphical glycan structures from structural inputs and nomenclature strings.
  • Dynamic nomenclature conversion: Converts bidirectionally between graphical glycan representations and linear nomenclature, generating visual structures from modified IUPAC-condensed names and vice versa.
  • Export formats: Exports glycan structures as SVG vector graphics and as condensed GlycoCT format for downstream analysis and sharing.

Scientific Applications:

  • Structural analysis: Visualizes and represents glycan structures to support analysis of glycan composition and potential biological interactions.
  • Data standardization: Produces standardized nomenclature and file-format outputs to enable consistent reporting and comparison of glycan data across studies.
  • Educational use: Provides an environment for learning glycan structure representation and nomenclature conventions.

Methodology:

Implemented in JavaScript and performs dynamic conversion between graphical glycan structures and modified IUPAC-condensed nomenclature with export to condensed GlycoCT and SVG using internal conversion algorithms.

Topics

Details

Tool Type:
web application
Programming Languages:
JavaScript
Added:
1/18/2021
Last Updated:
1/23/2021

Operations

Publications

Mehta AY, Cummings RD. GlycoGlyph: a glycan visualizing, drawing and naming application. Bioinformatics. 2020;36(11):3613-3614. doi:10.1093/bioinformatics/btaa190. PMID:32170934. PMCID:PMC7267839.

PMID: 32170934
PMCID: PMC7267839
Funding: - National Institutes of Health: P41GM103694, U01GM125267