GlyConnect

GlyConnect integrates and centralizes glycomics and glycoproteomics data to standardize and consolidate site-specific glycosylation patterns and diverse glycan structures and to enable linkage with proteomics, genomics, and interactomics datasets.

Key Features:

• Centralized aggregation: Gathers and monitors glycomics and glycoproteomics data, including supplemental tables and localized laboratory servers, within the Glycomics@ExPASy portal.
• Data standardization: Standardizes and consolidates glycomics and glycoproteomics datasets to harmonize representations of glycan structures and site-specific glycosylation.
• Site-specific glycosylation mapping: Accommodates glycoproteins with annotated, site-specific glycosylation patterns.
• Glycan structure representation: Captures and stores diverse glycan structures associated with glycoproteins.
• Cross-omics connectivity: Connects glycoscience data with proteomics, genomics, and interactomics datasets.
• Visualization and monitoring: Visualizes glycoscience data and monitors aggregated datasets.
• Search and display: Enables searching and display of consolidated glycomics and glycoproteomics information.

Scientific Applications:

• Glycoprotein characterization: Analysis of site-specific glycosylation patterns on glycoproteins.
• Comparative glycomics and glycoproteomics: Consolidation of datasets from publications and laboratory servers for comparative studies.
• Cross-omics analyses: Linking glycosylation information with proteomics, genomics, and interactomics to study molecular contexts.
• Disease-related glycosylation studies: Investigation of glycoprotein glycosylation patterns in health and disease.

Methodology:

GlyConnect computationally gathers, monitors, standardizes, consolidates, integrates, visualizes, searches, displays, and connects glycomics and glycoproteomics datasets.