GoaT

GoaT aggregates and indexes genome-relevant metadata across the eukaryotic tree of life to support coordination and prioritization of large-scale sequencing projects such as the Earth BioGenome Project's effort to generate reference-quality genome assemblies for approximately 1.9 million described eukaryotic taxa.

Key Features:

• Elasticsearch-powered datastore: Uses Elasticsearch to build a scalable search index for efficient querying, storage, and retrieval of genomic metadata.
• Comprehensive metadata indexing: Indexes publicly available genome-relevant metadata for all eukaryotic species, including over 70 taxon attributes and more than 30 assembly attributes.
• Phylogenetic interpolation of missing values: Interpolates missing taxon metadata by phylogenetic comparison to increase dataset completeness.
• Project coordination and tracking: Maintains target priorities and sequencing-status metadata for projects affiliated with the Earth BioGenome Project.

Scientific Applications:

• Project planning and prioritization: Inform target selection and prioritization for large-scale genome-sequencing initiatives such as the Earth BioGenome Project.
• Metadata aggregation and reporting: Aggregate and report genome-relevant metadata across the eukaryotic tree of life to support comparative studies and resource planning.
• Data completeness and inference: Provide interpolated attribute values to enable analyses that require more complete taxon metadata.
• Sequencing progress tracking: Track sequencing statuses and project priorities to support coordination of multi-project sequencing efforts.

Methodology:

Aggregates publicly available genome-relevant metadata, indexes the data using Elasticsearch, applies phylogenetic comparison to interpolate missing values, and records project-level target priorities and sequencing-status metadata.