GOLD

GOLD provides a curated repository of metadata for genome and metagenome sequencing projects managed by the Department of Energy Joint Genome Institute (DOE-JGI) to support comparative genomics, microbial ecology, and environmental genomics.


Key Features:

  • Extensive metadata repository: GOLD compiles project-level information and associated metadata for genome and metagenome sequencing projects.
  • Public API: GOLD exposes programmatic access for data retrieval and integration with external bioinformatics tools and pipelines.
  • Versioned expansions: Iterative releases (for example GOLD v.9) expand project coverage and metadata scope.

Scientific Applications:

  • Comparative genomics: Supports large-scale comparative analyses by providing standardized project metadata across genomes and metagenomes.
  • Evolutionary studies: Provides project context and sequencing metadata useful for phylogenetic and evolutionary inference.
  • Microbial ecology: Enables ecological analyses by aggregating project metadata relevant to microbial community studies.
  • Environmental genomics: Aggregates metagenome project metadata to support cross-habitat and environmental genomics investigations.

Methodology:

GOLD systematically curates metadata from genome and metagenome sequencing projects and exposes the curated metadata via a public API.

Topics

Details

License:
Other
Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Java, Python, Bash, Perl
Added:
1/28/2023
Last Updated:
1/28/2023

Operations

Publications

Mukherjee S, Stamatis D, Li CT, Ovchinnikova G, Bertsch J, Sundaramurthi JC, Kandimalla M, Nicolopoulos PA, Favognano A, Chen IA, Kyrpides NC, Reddy TBK. Twenty-five years of Genomes OnLine Database (GOLD): data updates and new features in v.9. Nucleic Acids Research. 2022;51(D1):D957-D963. doi:10.1093/nar/gkac974. PMID:36318257. PMCID:PMC9825498.

PMID: 36318257
PMCID: PMC9825498
Funding: - U.S. Department of Energy: DE-AC02-05CH11231 - Biological and Environmental Research: 89233218CNA000001, DE-AC02-05CH11231, DE-AC05-00OR22725, DE-AC05-76RL01830

Links