GoMapMan

GoMapMan provides MapMan-based functional annotation, consolidation, and visualization of gene functions across multiple plant species to support comparative genomics and high-throughput analyses.

Key Features:

• Dynamic and interactive annotation: Supports dynamic, curator-driven annotation of gene products with multiple curation options.
• Cross-species consolidation: Consolidates gene annotations across species by integrating orthologue group information for organisms including Arabidopsis, potato, tomato, and rice.
• Traceability of ontology changes: Records and ensures traceability of changes to gene ontology annotations.
• Integration of external knowledge: Incorporates external public gene knowledge sources to enrich internal annotations.
• Export for high-throughput analysis: Dynamically generates export files containing collected annotations and orthologue data for large-scale analyses.

Scientific Applications:

• Functional annotation: Assigns and consolidates functional annotations for plant genes using MapMan ontology terms.
• Comparative functional genomics: Enables cross-species comparison and inference of gene function via orthologue group integration.
• Annotation provenance and auditing: Provides a record of annotation changes to support provenance and historical analysis of gene ontology updates.
• Data enrichment: Augments gene annotations with information from external public resources to improve functional interpretation.
• Preparation for large-scale analyses: Produces exportable datasets suitable for downstream high-throughput computational analyses.

Methodology:

Leverages the hierarchical MapMan ontology, integrates orthologue group information and external public gene resources, records changes to gene ontology annotations for traceability, and dynamically generates export files.