GPMDB API

GPMDB API provides programmatic access to experimental proteomics data in the Global Proteome Machine Database, enabling retrieval of protein post-translational modifications, amino acid variants, alternate splicing variants, and protein cleavage patterns for computational proteomics research.

Key Features:

• RESTful interface: Implements Representational State Transfer (REST) for standardized programmatic access to GPMDB.
• Proteomics data access: Retrieves experimental data on protein post-translational modifications, amino acid variants, alternate splicing variants, and protein cleavage patterns.
• Query methods: Version 1 exposes 25 distinct, stable methods and parameters for querying the database and ensuring consistent data retrieval.

Scientific Applications:

• Protein Function Analysis: Enables analysis of how post-translational modifications affect protein function using experimental evidence from GPMDB.
• Disease Research: Supports investigation of amino acid variants implicated in disease mechanisms.
• Genomic Studies: Facilitates exploration of alternate splicing and its implications for gene expression regulation.

Methodology:

The API implements a RESTful interface with a stable set of 25 methods and parameters for standardized, consistent querying and data retrieval.