GproteinDb

GproteinDb provides a reference database and analytical resources for G proteins and receptors that couple with G proteins, supporting pharmacological, structural, and genomic research.


Key Features:

  • Extensive Reference Data: Compiles data on G proteins, receptors that couple with G proteins, signaling substances, and pharmaceutical drugs.
  • Analytical Tools: Offers tools for analysis of G protein signaling pathways and for pharmacological, structural, and genomic investigations.
  • Visualization Capabilities: Provides visualization of complex signaling, structural, and genomic datasets related to G proteins.
  • Study Design Support: Supplies resources to support experimental study design for investigating G protein function.

Scientific Applications:

  • Translational Analysis: Translates pharmacological, structural, and genomic data into insights on G protein signaling relevant to human physiology and medical interventions.
  • Drug Discovery: Supports identification and characterization of drug–receptor interactions mediated by G proteins.
  • Sensory System Research: Enables investigation of sensory systems that operate via G protein signaling.
  • Cellular Communication: Facilitates exploration of cellular communication mechanisms mediated by G proteins.

Methodology:

Integration of diverse data types related to G proteins into a cohesive online resource.

Topics

Collections

Details

Cost:
Free of charge
Tool Type:
web application
Added:
2/8/2024
Last Updated:
2/15/2024

Operations

Publications

Pándy-Szekeres G, Esguerra M, Hauser AS, Caroli J, Munk C, Pilger S, Keserű GM, Kooistra AJ, Gloriam DE. The G protein database, GproteinDb. Nucleic Acids Research. 2021;50(D1):D518-D525. doi:10.1093/nar/gkab852. PMID:34570219. PMCID:PMC8728128.

Funding: - Independent Research Fund Denmark: 8021-00173B - Lundbeck Foundation: R218-2016-1266 - Novo Nordisk Foundation: NNF18OC0031226 - Hungarian Brain Research Program: 2017-1.2.1-NKP-2017-00002