GproteinDb
GproteinDb provides a reference database and analytical resources for G proteins and receptors that couple with G proteins, supporting pharmacological, structural, and genomic research.
Key Features:
- Extensive Reference Data: Compiles data on G proteins, receptors that couple with G proteins, signaling substances, and pharmaceutical drugs.
- Analytical Tools: Offers tools for analysis of G protein signaling pathways and for pharmacological, structural, and genomic investigations.
- Visualization Capabilities: Provides visualization of complex signaling, structural, and genomic datasets related to G proteins.
- Study Design Support: Supplies resources to support experimental study design for investigating G protein function.
Scientific Applications:
- Translational Analysis: Translates pharmacological, structural, and genomic data into insights on G protein signaling relevant to human physiology and medical interventions.
- Drug Discovery: Supports identification and characterization of drug–receptor interactions mediated by G proteins.
- Sensory System Research: Enables investigation of sensory systems that operate via G protein signaling.
- Cellular Communication: Facilitates exploration of cellular communication mechanisms mediated by G proteins.
Methodology:
Integration of diverse data types related to G proteins into a cohesive online resource.
Topics
Collections
Details
- Cost:
- Free of charge
- Tool Type:
- web application
- Added:
- 2/8/2024
- Last Updated:
- 2/15/2024
Operations
Publications
Pándy-Szekeres G, Esguerra M, Hauser AS, Caroli J, Munk C, Pilger S, Keserű GM, Kooistra AJ, Gloriam DE. The G protein database, GproteinDb. Nucleic Acids Research. 2021;50(D1):D518-D525. doi:10.1093/nar/gkab852. PMID:34570219. PMCID:PMC8728128.
DOI: 10.1093/nar/gkab852
Funding: - Independent Research Fund Denmark: 8021-00173B
- Lundbeck Foundation: R218-2016-1266
- Novo Nordisk Foundation: NNF18OC0031226
- Hungarian Brain Research Program: 2017-1.2.1-NKP-2017-00002