graph

graph provides graph data-structure handling and manipulation in R to represent and analyze biological networks and relationships in high-throughput genomic and molecular biology data.


Key Features:

  • Graph data structures: Implements simple graph handling capabilities to manage and manipulate graph data structures.
  • Representation of relationships: Encodes complex relationships within biological datasets for network-based analysis.
  • Network modeling support: Supports modeling and analysis of gene regulatory networks, protein-protein interaction networks, and metabolic pathways.
  • Bioconductor integration: Implemented as an R package within the Bioconductor project and interoperable with other Bioconductor packages.

Scientific Applications:

  • Gene regulatory network analysis: Uses graph representations to model and analyze regulatory relationships among genes.
  • Protein-protein interaction analysis: Represents protein-protein interaction networks to explore molecular interactions.
  • Metabolic pathway representation: Represents metabolic pathways as graphs for pathway-level analysis and interpretation.
  • Network-based representation of biological data: Enables encoding and exploration of complex biological relationships in high-throughput genomic and molecular biology datasets.

Methodology:

The input does not specify computational algorithms or stepwise processing methods.

Topics

Collections

Details

License:
Artistic-2.0
Tool Type:
command-line tool, library
Operating Systems:
Linux, Windows, Mac
Programming Languages:
R
Added:
1/17/2017
Last Updated:
11/25/2024

Operations

Publications

Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.

Documentation

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