GVAF

GVAF filters annotated variant files in any table-shaped format using flexible filtering operations without requiring additional software or programming expertise.

Key Features:

• Flexible Filtering Rules: GVAF provides powerful filtering operations for annotated variant data.
• VCF Genotype Recognition: GVAF recognizes genotype-related fields from variant call format (VCF) files.
• Customizable Result Generation: GVAF allows users to customize how results are generated.
• Pipeline Integration: GVAF integrates easily into existing data analysis pipelines.

Scientific Applications:

• Variant Interpretation: GVAF streamlines the interpretation of genetic variants from next-generation sequencing (NGS) data.
• Multi-format Variant Filtering: GVAF filters annotated variant files produced by diverse variant annotation tools.

Methodology:

GVAF is built on the Java framework and bash scripts.