HaloDom

HaloDom aggregates curated taxonomic, halotolerance, genomic, proteomic, and bibliographic data on halophilic organisms to support comparative genomics, evolutionary studies, and biotechnological research.

Key Features:

• Species coverage: Documents over 1,000 halophilic species across Archaea, Bacteria, and Eukarya.
• Taxonomic classification: Provides detailed taxonomy information for each halophilic species, including domain-level assignment to Archaea, Bacteria, or Eukarya.
• Halotolerance data: Includes salinity metadata specifying the salt concentrations at which each organism can survive or thrive.
• Genomic and proteomic links: Offers direct links to genomic and proteomic information via NCBI and other relevant databases.
• Publication information: Compiles bibliographic references associated with each halophilic organism.
• Curated entries: Maintains curated records derived from the primary scientific literature.

Scientific Applications:

• Biotechnology: Enables exploration of halophile-derived enzymes and pathways for enzyme production, biofuel generation, and bioremediation applications.
• Early life evolution studies: Supports analyses of halophile diversity and characteristics to infer environmental conditions relevant to early life on Earth.
• Comparative genomics: Facilitates comparative genomic analyses across halophiles from multiple domains to investigate evolutionary processes and gene function.

Methodology:

Data were compiled through an extensive literature review to identify and document over 1,000 halophilic species, which were categorized as 21.9% Archaea, 50.1% Bacteria, and 27.9% Eukaryotes, and the collection is updated with new findings from the scientific literature.