HEAP

HEAP automates identification and quantification of microscopic helminth eggs using deep learning to support parasitology diagnostics.


Key Features:

  • Model architectures: Implements SSD (Single Shot MultiBox Detector), U-net, and Faster R-CNN (Faster Region-based Convolutional Neural Network).
  • Model selection: Allows selection of the most suitable prediction model for a given specimen or analysis task.
  • Image binning and egg-in-edge algorithm: Employs pixel density detection to enhance microscopic image resolution and improve egg identification performance.
  • Distributed computing: Supports distributed computing across various operating systems to reduce computation time and operate on low-cost computers.
  • Parasitic egg database: Includes a collection of microscopic helminth egg images with associated labeling data and pretrained models.
  • Automated quantification: Provides automated counting and quantification of helminth eggs from microscopic specimens.

Scientific Applications:

  • Parasitology diagnostics: Automated image-based detection and counting of helminth eggs to support diagnostic workflows.
  • Research and model development: Uses labeled image datasets and pretrained models for development and validation of deep learning approaches in parasitology.
  • Training and education: Serves as a resource for training technicians and students in microscopic helminth egg examination.
  • Field and low-resource screening: Enables deployment of automated egg detection and quantification on low-cost computers in resource-limited laboratory settings.

Methodology:

Integrates SSD, U-net, and Faster R-CNN architectures; applies image binning and an egg-in-edge algorithm using pixel density detection; operates via distributed computing across multiple operating systems and provides labeled datasets and pretrained models.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
3/1/2022
Last Updated:
3/1/2022

Operations

Publications

Lee C, Huang P, Yeh Y, Li P, Chiu C, Cheng W, Tang P. Helminth egg analysis platform (HEAP): An opened platform for microscopic helminth egg identification and quantification based on the integration of deep learning architectures. Journal of Microbiology, Immunology and Infection. 2022;55(3):395-404. doi:10.1016/j.jmii.2021.07.014. PMID:34511389.

PMID: 34511389
Funding: - Chang Gung University: BMRP056 - Ministry of Science and Technology, Taiwan: 109-2221-E-182-049, 110-2221-E-182-048 - Chang Gung Memorial Hospital: CORPD2J0051