Hiplot

Hiplot provides over 240 data visualization functions and analytical methods to visualize and analyze complex biomedical data from clinical studies, omics research, and mechanism-based experiments.

Key Features:

• Visualization functions: Over 240 specialized data visualization functions producing high-quality, publication-ready graphics.
• Analytical methods: Support for basic statistics, multi-omics integration, regression analysis, clustering, dimensional reduction, meta-analysis, survival analysis, and risk modeling.
• Data import: Spreadsheet-based data importing for tabular datasets.
• Command-line controller (Hctl): A cross-platform command-line controller (Hctl) for programmatic control.
• Server-side processing: Multi-user plumber workers for concurrent server-side processing.
• Plugin system: JavaScript Object Notation (JSON)-based plugin system for extensibility.
• Reproducibility and updates: Reproduction of data, parameters, results, and errors, with support for real-time updates.

Scientific Applications:

• Clinical and experimental data visualization: Visualizing complex datasets from clinical studies and mechanism-based experiments.
• Omics research and integration: Integrating and exploring multi-omics datasets for comparative and integrative analyses.
• Cancer genomics: Exploration and visualization of cancer genomic landscapes.
• Risk and survival studies: Statistical exploration of disease risk factors, survival analysis, and risk modeling.
• Exploratory analysis and figure generation: Generation of figures for exploratory analysis, presentation, and publication.

Methodology:

Implements spreadsheet-based data importing, a cross-platform command-line controller (Hctl), multi-user plumber workers, a JSON-based plugin system, and computational methods including basic statistics, multi-omics integration, regression, clustering, dimensional reduction, meta-analysis, survival analysis, and risk modeling, while recording data, parameters, results, and errors for reproducibility and supporting real-time updates.