HODD

HODD consolidates curated information on human ophthalmic diseases, associated genetic variants, and symptom characteristics to support genetic and clinical research and diagnosis.

Key Features:

• Extensive Disease Coverage: HODD encompasses 730 distinct ophthalmic diseases.
• Genetic Information: The database includes information on 653 genes associated with these diseases, including gene locations and roles in ocular and extraocular manifestations.
• Data Integration: Information is aggregated from several well-established databases.
• Detailed Disease Profiles: Each disease entry includes a description, related genes, protein-protein interactions, and associated pathways.

Scientific Applications:

• Facilitating Research: Centralizing diverse datasets enables exploration of genetic correlations and biological pathways in ophthalmic disease research.
• Enhancing Diagnosis: The compiled symptom characteristics and genetic information support clinical interpretation and differential diagnosis of complex eye disorders.

Methodology:

Collected disease-related information and gene data from multiple reputable sources and systematically reorganized the data.