hypeR

hypeR performs geneset enrichment analyses to annotate high-throughput sequencing data.

Key Features:

• Comprehensive Workflow Support: Supports multiple enrichment methods enabling analyses across diverse datasets and experimental conditions.
• Hierarchical Geneset Analysis: Enables hierarchical geneset analysis to explore nested relationships among gene sets.
• Visualization Tools: Provides visualization functions for interpreting enrichment results.
• Built-in Markdown Reporting: Generates Markdown reports summarizing enrichment results.
• Multi-Experiment Analysis: Handles multiple signatures across numerous experiments for large-scale studies.

Scientific Applications:

• Genomics and bioinformatics: Annotation and interpretation of high-throughput sequencing datasets via geneset enrichment analyses.

Methodology:

Implemented in R and requires R >= 3.6.0; it may run on R >= 3.5.0 but earlier versions are not recommended due to potential compatibility issues.