hypergraph
hypergraph represents and manipulates hypergraphs to model multi-way relationships in high-throughput genomic and molecular biology datasets using R within the Bioconductor ecosystem.
Key Features:
- Hypergraph Representation: Represents hypergraphs where edges can connect any number of vertices to model complex multi-way biological interactions.
- Manipulation Capabilities: Provides functions to modify and analyze hypergraph structures for downstream computational analyses.
- Bioconductor Integration: Implemented in R and interoperable within the Bioconductor ecosystem as one of the 934 Bioconductor packages.
Scientific Applications:
- Genomics and Molecular Biology: Models gene regulatory networks, protein-protein interaction networks, and other multi-way interactions from high-throughput genomic and molecular data.
- Interdisciplinary Network Analysis: Enables exploration of multifaceted relationships that traditional graph models may not capture across diverse biological datasets.
Methodology:
Implemented in R with integration into Bioconductor; the package undergoes formal initial review and continuous automated testing by the Bioconductor community.
Topics
Collections
Details
- License:
- Artistic-2.0
- Tool Type:
- command-line tool, library
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- R
- Added:
- 1/17/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Huber W, Carey VJ, Gentleman R, Anders S, Carlson M, Carvalho BS, Bravo HC, Davis S, Gatto L, Girke T, Gottardo R, Hahne F, Hansen KD, Irizarry RA, Lawrence M, Love MI, MacDonald J, Obenchain V, Oleś AK, Pagès H, Reyes A, Shannon P, Smyth GK, Tenenbaum D, Waldron L, Morgan M. Orchestrating high-throughput genomic analysis with Bioconductor. Nature Methods. 2015;12(2):115-121. doi:10.1038/nmeth.3252. PMID:25633503. PMCID:PMC4509590.