iEEGview

iEEGview localizes and visualizes human intracranial electrodes to support analysis of intracranial electroencephalography (iEEG) data.

Key Features:

• Integrated localization pipeline: Processes pre-implant MRI and post-implant CT including brain segmentation, image co-registration, and electrode reconstruction.
• Anatomical information and activation maps: Generates activation maps and provides anatomical labels for electrodes in native brain space.
• Projection to common brain spaces: Projects electrodes from native space into common brain spaces to enable group analysis.
• Brain shift correction: Applies correction methods to compensate for brain shift after implantation.
• Certainty index computation: Computes a certainty index to quantify confidence in anatomical label assignments.
• Matlab implementation: Implements processing and analyses as Matlab scripts.

Scientific Applications:

• Epilepsy research: Supports localization and analysis of epileptic activity using intracranial recordings.
• Brain–computer interface studies: Provides electrode localization needed for BCI signal interpretation and system development.
• Cognitive neuroscience: Enables mapping of neural activity underlying cognitive functions using iEEG.
• Group-level analyses: Facilitates group comparisons by projecting electrode data into common brain spaces.
• Neural activity and connectivity analysis: Supports detailed analysis of neural activity patterns and connectivity from intracranial recordings.

Methodology:

Processes pre-implant MRI and post-implant CT through brain segmentation, image co-registration, electrode reconstruction, brain shift correction, projection to common brain spaces, activation map generation, and certainty index computation implemented in Matlab.