iRODS

iRODS manages rule-based organization, metadata, and access control for large-scale next-generation sequencing (NGS) datasets to support cancer genome analysis.


Key Features:

  • Metadata Management: Customizable metadata attributes via an open-source metadata management system to track and organize NGS datasets.
  • Data Security: Fine-grained, rule-based protection rules and access controls to safeguard sensitive genomic data.
  • Centralized Storage: Unified, scalable storage management for large volumes of NGS data within high-performance computing environments.

Scientific Applications:

  • Cancer Genomics: Provides secure storage, detailed metadata tracking, and controlled access for datasets used in cancer genome analysis, reproducibility, and validation.
  • Genome Analysis Pipelines: Integrates with genome analysis pipelines in high-performance computing environments to enable centralized data and metadata access across research teams.

Methodology:

Deployment within high-performance computing environments combining customizable metadata management, rule-based protection protocols, and centralized storage to provide unified access to NGS dataset metadata.

Topics

Details

License:
BSD-3-Clause
Maturity:
Mature
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Linux, Mac
Added:
5/25/2019
Last Updated:
6/16/2020

Operations

Publications

Nieroda L, Maas L, Thiebes S, Lang U, Sunyaev A, Achter V, Peifer M. iRODS metadata management for a cancer genome analysis workflow. BMC Bioinformatics. 2019;20(1). doi:10.1186/s12859-018-2576-5. PMID:30646845. PMCID:PMC6334444.

Documentation