IBRtools

IBRtools calculates Integrated Biomarker Response (IBR) and Integrated Biological Responses version 2 (IBRv2) indexes for multibiomarker studies evaluating early warning signs of environmental degradation.

Key Features:

• IBR and IBRv2 Calculation: The package includes functions for calculating both IBR and IBRv2 indexes while simultaneously incorporating all biomarkers under evaluation.
• Standardized Values: Functions obtain standardized values for the calculated indexes.
• Radar Chart Creation: A function generates radar charts for visualization of results.
• Example Datasets: Three example datasets are included to illustrate workflow and guide accurate index calculation.

Scientific Applications:

• Environmental Degradation Assessment: IBRtools evaluates early warning signs of environmental degradation through unified multibiomarker responses.
• Large-Scale Biomarker Analysis: The package handles large datasets for straightforward IBR and IBRv2 index acquisition in environmental toxicology studies.

Methodology:

The main algorithms involved in IBR and IBRv2 calculations are implemented to compute index values from multibiomarker data.