iCRF Generator

iCRF Generator generates interoperable electronic case report forms (iCRFs) for clinical research by mapping codebook items to standardized terminologies such as SNOMED CT and producing outputs aligned with HL7 and functional information standards.

Key Features:

• Implementation: Java-based application.
• iCRF generation: Generates core components of interoperable electronic case report forms for OpenClinica 3, Castor, and REDCap.
• Codebook mapping: Allows selection of items from established codebooks that are pre-mapped to SNOMED CT.
• Repository integration: Accesses codebooks via the ART-DECOR online repository.
• Standards compliance: Produces outputs aligned with HL7 and functional information standards to support semantic interoperability.

Scientific Applications:

• Semantic interoperability: Preserves clinical data meaning and intent across systems for exchange, reuse, and integration.
• Cross-EDC harmonization: Enables generation of CRFs consistent across OpenClinica 3, Castor, and REDCap to facilitate data integration.
• Clinical research data exchange: Supports structured, standardized data capture to enhance exchange and reuse in clinical trials and research studies.

Methodology:

Java-based generation of iCRF core components for OpenClinica 3, Castor, and REDCap using codebook items pre-mapped to SNOMED CT accessed from ART-DECOR, with outputs aligned to HL7 and functional information standards.