ID History converter

ID History converter converts Ensembl IDs between Ensembl releases to map gene, transcript, and protein identifiers across database versions for genomic analyses.

Key Features:

• ID Conversion Across Releases: Maps Ensembl IDs from previous releases to current equivalents to maintain identifier continuity.
• Integration with Ensembl's Comprehensive Databases: Leverages Ensembl datasets covering 87 species and updates for humans, mice, zebrafish, and rats to reflect current genomic assemblies.
• Support for Historical Data: Provides access to resources for previous genome assemblies such as the human assembly GRCh37.
• Enhanced Tool Integration: Integrates with the Variant Effect Predictor (VEP) and BioMart and supports incorporation of third-party annotation data.
• Scalability via RESTful Services: Uses RESTful services to support large-scale ID mapping and manage extensive datasets.

Scientific Applications:

• Genomic Research: Facilitates accurate tracking and updating of genomic identifiers across Ensembl releases.
• Comparative Genomics: Enables comparison of genomic information across species and assemblies without identifier inconsistencies.
• Longitudinal Studies: Supports analyses that require consistent reference identifiers over time despite database version changes.

Methodology:

Uses Ensembl's regularly updated datasets, integrates with VEP for variant analysis and BioMart for regulatory data access, and employs RESTful services for large-scale ID mapping.