IGDD

IGDD provides a curated repository of mutation, clinical, and biochemical data for genetic diseases observed in Indian populations to support genetic research, clinical diagnostics, and population-level analyses.

Key Features:

• Extensive Coverage: Contains data for 52 distinct genetic diseases and records from 5,760 individuals carrying mutant alleles in causal genes.
• Comprehensive Data Integration: Includes locus heterogeneity, mutation types, and associated clinical and biochemical data for each disease.
• Geographical Insights: Associates patient and carrier records with geographical location to enable analysis of regional mutation prevalence and distribution across India.
• Search Functionality: Supports queries by disease, causal gene, type of mutation, and geographical location.
• Data Deposition and Updates: Structured to accommodate ongoing data deposition and regular updates of mutation records.

Scientific Applications:

• Genetic Research: Facilitates studies on the genetic basis of diseases in Indian populations, including effects of endogamous groups on recessive disease prevalence.
• Clinical Diagnostics: Supports healthcare professionals in diagnosing genetic disorders by providing detailed mutation and clinical data.
• Public Health Planning: Informs public health strategies by providing insights into disease prevalence and regional distribution.

Methodology:

Data are curated and compiled from published literature.