IMG_VR

IMG_VR catalogs over 15 million virus genomes and genome fragments from genomes, metagenomes, and metatranscriptomes to support comparative viral genomics and diversity studies.

Key Features:

• Extensive Database: Contains over 15 million viral genomes and genome fragments organized into 8.7 million viral operational taxonomic units (vOTUs), including 231,408 vOTUs with at least one high-quality representative genome.
• Data Sources: Sequences are derived from isolate genomes, metagenomes, and metatranscriptomes, enabling cross-environment viral diversity sampling.
• Advanced Detection Methodology: Uses the geNomad detection approach to identify viral sequences across diverse datasets.
• Functional Annotation and Metadata: Provides functional annotations along with genome quality assessments using CheckV, taxonomic classifications aligned with current standards, and microbial host taxonomy predictions.

Scientific Applications:

• Ecological Studies: Enables investigation of viral roles and interactions within microbial communities across environments.
• Evolutionary Biology: Facilitates analyses of viral evolution, diversification, and phylogenetic relationships using large-scale genomic data.
• Biotechnological Applications: Supplies annotated viral genes and genomes that can be mined for biotechnological and therapeutic research.

Methodology:

Viral sequence detection with geNomad; organization into vOTUs; genome quality assessment with CheckV; taxonomic classification aligned with current standards; and prediction of microbial host taxonomy.