Integrated Microbial Genomes (IMG)

Integrated Microbial Genomes (IMG) provides comparative analysis of publicly available microbial genomes and supports analysis and review of gene and genome annotations across draft and complete genomes, plasmids, and viruses from the three domains of life.


Key Features:

  • Genome collection: Contains draft and complete microbial genomes, plasmids, and viruses from the three domains of life.
  • Comparative analysis framework: Enables integrated comparative analysis of publicly available genomes.
  • Annotation analysis and review: Facilitates analysis and expert review of gene and genome annotations within a comparative context.
  • Analytical tools and viewers: Provides an array of analysis tools and viewers tailored for comparative genomic analyses.
  • IMG/ER (Expert Review): Supports expert review and curation of genome annotations.
  • IMG/HMP: Supports analysis of genomes related to the Human Microbiome Project for human-associated microbial community studies.
  • Regular updates: Expands data content and analytical capabilities through regular updates.

Scientific Applications:

  • Comparative genomics: Comparative genomic studies across microbial genomes from the three domains of life.
  • Annotation curation: Expert review and curation of gene and genome annotations to improve annotation quality.
  • Human microbiome research: Analysis of genomes related to the Human Microbiome Project to investigate human-associated microbial communities.
  • Plasmid and viral genomics: Comparative and annotation analyses focused on plasmids and viruses.

Methodology:

Performs comparative analysis of genomes and analysis/review of gene and genome annotations using IMG's suite of analysis tools and viewers, with expert curation via IMG/ER.

Topics

Details

Tool Type:
web application
Added:
3/30/2017
Last Updated:
11/24/2024

Operations

Publications

Markowitz VM, Chen IA, Palaniappan K, Chu K, Szeto E, Grechkin Y, Ratner A, Anderson I, Lykidis A, Mavromatis K, Ivanova NN, Kyrpides NC. The integrated microbial genomes system: an expanding comparative analysis resource. Nucleic Acids Research. 2009;38(suppl_1):D382-D390. doi:10.1093/nar/gkp887. PMID:19864254. PMCID:PMC2808961.

Markowitz VM, Chen IA, Palaniappan K, Chu K, Szeto E, Grechkin Y, Ratner A, Jacob B, Huang J, Williams P, Huntemann M, Anderson I, Mavromatis K, Ivanova NN, Kyrpides NC. IMG: the integrated microbial genomes database and comparative analysis system. Nucleic Acids Research. 2011;40(D1):D115-D122. doi:10.1093/nar/gkr1044. PMID:22194640. PMCID:PMC3245086.