UK Veterinary Immunological Toolbox Website
UK Veterinary Immunological Toolbox Website provides an open-access repository of species-specific immunological reagents and associated annotations to support veterinary immunology research, vaccine studies, and investigations of zoonotic pathogens.
Key Features:
- Comprehensive Reagent Repository: Maintains a collection of antibodies and other reagents tailored to veterinary species, with emphasis on livestock.
- Model Enhancement: Supports selection and application of animal models for studying immune responses and developing vaccination strategies.
- Community-Annotated Hub: Aggregates researcher-contributed annotations and reagent metadata for veterinary immunological reagents.
- Service Integration: Provides services including antibody generation, sequencing, and recombinant expression.
Scientific Applications:
- Veterinary immunology research: Enables characterization of immune responses across veterinary species using species-specific reagents.
- Vaccine development and evaluation: Supports evaluation of immune responses to vaccine candidates using validated antibodies and reagents.
- Zoonotic pathogen research: Facilitates studies of zoonotic pathogens using livestock models relevant to animal and human health.
- Reagent validation and assay development: Enables antibody validation, sequencing-based characterization, and recombinant expression for assay development.
Methodology:
Services explicitly include antibody generation, sequencing, and recombinant expression, and reagent information is curated through community-contributed annotations.
Topics
Details
- Added:
- 1/18/2021
- Last Updated:
- 3/6/2021
Operations
Publications
Mwangi W, Maccari G, Hope JC, Entrican G, Hammond JA. The UK Veterinary Immunological Toolbox Website: promoting vaccine research by facilitating communication and removing reagent barriers. Immunology. 2020;161(1):25-27. doi:10.1111/imm.13227. PMID:32548865. PMCID:PMC7450168.
DOI: 10.1111/IMM.13227
PMID: 32548865
PMCID: PMC7450168
Funding: - SG RESAS Strategic Research Programme, UKRI-BBSRC/SG/BioRad: BB/I019863/1
- European Union Horizon 2020: 731014
- UKRI-BBSRC: BB/I020519/1, BB/P013740/1, BBS/, BBS/E/D/20002174, BBS/E/I/00007038, BBS/E/I/00007039, BBS/OS/GC/000015, E/I/00007030
- BMGF: OPP1215550