UK Veterinary Immunological Toolbox Website

UK Veterinary Immunological Toolbox Website provides an open-access repository of species-specific immunological reagents and associated annotations to support veterinary immunology research, vaccine studies, and investigations of zoonotic pathogens.


Key Features:

  • Comprehensive Reagent Repository: Maintains a collection of antibodies and other reagents tailored to veterinary species, with emphasis on livestock.
  • Model Enhancement: Supports selection and application of animal models for studying immune responses and developing vaccination strategies.
  • Community-Annotated Hub: Aggregates researcher-contributed annotations and reagent metadata for veterinary immunological reagents.
  • Service Integration: Provides services including antibody generation, sequencing, and recombinant expression.

Scientific Applications:

  • Veterinary immunology research: Enables characterization of immune responses across veterinary species using species-specific reagents.
  • Vaccine development and evaluation: Supports evaluation of immune responses to vaccine candidates using validated antibodies and reagents.
  • Zoonotic pathogen research: Facilitates studies of zoonotic pathogens using livestock models relevant to animal and human health.
  • Reagent validation and assay development: Enables antibody validation, sequencing-based characterization, and recombinant expression for assay development.

Methodology:

Services explicitly include antibody generation, sequencing, and recombinant expression, and reagent information is curated through community-contributed annotations.

Topics

Details

Added:
1/18/2021
Last Updated:
3/6/2021

Operations

Publications

Mwangi W, Maccari G, Hope JC, Entrican G, Hammond JA. The UK Veterinary Immunological Toolbox Website: promoting vaccine research by facilitating communication and removing reagent barriers. Immunology. 2020;161(1):25-27. doi:10.1111/imm.13227. PMID:32548865. PMCID:PMC7450168.

PMID: 32548865
PMCID: PMC7450168
Funding: - SG RESAS Strategic Research Programme, UKRI-BBSRC/SG/BioRad: BB/I019863/1 - European Union Horizon 2020: 731014 - UKRI-BBSRC: BB/I020519/1, BB/P013740/1, BBS/, BBS/E/D/20002174, BBS/E/I/00007038, BBS/E/I/00007039, BBS/OS/GC/000015, E/I/00007030 - BMGF: OPP1215550

Links