IndiGenomes

IndiGenomes provides a compendium of 55,898,122 single allelic genetic variants derived from whole genome sequencing of 1,029 geographically diverse healthy Indian individuals to support population-scale genomic analyses and medical genetics.

Key Features:

• Extensive Variant Compendium: Contains 55,898,122 single allelic genetic variants identified from whole genome sequencing of 1,029 individuals.
• Variant-level Metrics: Reports allele frequency, allele count, and counts of heterozygous and homozygous individuals for each variant.
• Cohort Composition: Dataset comprises 1,029 healthy individuals sampled across geographically diverse regions of India.
• Systematic Annotation: Variants are annotated using publicly available population databases.

Scientific Applications:

• Genetic Diversity Studies: Enables analysis of population structure and identification of population-specific genetic markers within India.
• Medical Genetics and Personalized Medicine: Provides population-specific variant frequency data to inform clinical interpretation and personalized-risk assessments.
• Comparative Genomics: Supports comparative analyses between the Indian genomic landscape and other global populations.

Methodology:

Whole genome sequencing of 1,029 healthy Indian individuals was performed, variants were identified, and variants were annotated using existing population databases.