Insyght
Insyght visualizes comparative bacterial genomes to identify homologies, syntenies, and gene annotations across multiple complete bacterial genomes, including 2688 genomes from Ensembl.
Key Features:
- Synchronized Navigation Across Genomic Data: Synchronizes navigation across multiple genomes to enable direct comparison of homologous regions and syntenic blocks.
- Versatile Interoperability Between Complementary Views: Integrates complementary views to cross-link gene annotations, homology relationships, and synteny representations.
- Expanded Phylogenetic Coverage: Incorporates 2688 complete bacterial genomes from Ensembl to support broad phylogenetic comparative analyses.
Scientific Applications:
- Phylogenetic Analysis: Explores evolutionary relationships and lineage differentiation among bacterial species using comparative genome data.
- Gene Annotation Studies: Supports annotation by comparing homologous sequences across genomes to inform functional inference.
- Synteny Mapping: Identifies conserved gene order and syntenic blocks among bacterial genomes to study genome organization and evolution.
Methodology:
Implements a comparative visualization approach that integrates genomic data from multiple sources by synchronizing navigation across datasets and interoperating complementary views, with a dataset including 2688 Ensembl bacterial genomes.
Topics
Details
- Tool Type:
- command-line tool
- Operating Systems:
- Linux, Windows, Mac
- Programming Languages:
- JavaScript, SQL
- Added:
- 8/3/2017
- Last Updated:
- 11/25/2024
Operations
Publications
Lacroix T, Thérond S, Rugeri M, Nicolas P, Gendrault A, Loux V, Gibrat J. Synchronized navigation and comparative analyses across Ensembl complete bacterial genomes with INSYGHT. Bioinformatics. 2015;32(7):1083-1084. doi:10.1093/bioinformatics/btv689. PMID:26607491. PMCID:PMC4896367.