Intergr8

Intergr8 provides integrated genomic and proteomic data and annotations for organisms with completely sequenced genomes to support comparative genomics, functional annotation, and statistical analysis.

Key Features:

• Access to Comprehensive Data: Provides general organism information and a curated collection of recent publications relevant to genomic and proteomic studies.
• Statistical Overviews: Generates statistical analyses and overviews of genome and proteome properties to support comparative genomics and evolutionary studies.
• Data Integration from Multiple Sources: Integrates datasets and annotations from EMBL Nucleotide Sequence Database, UniProt Knowledgebase, InterPro, CluSTr, GOA (Gene Ontology Annotation), and HOGENOM.
• Customizable Interactive Analysis: Enables customization of analyses and tailoring of datasets to specific research needs.
• Downloadable Datasets: Supports export of customized and pre-prepared datasets for downstream analysis.

Scientific Applications:

• Genomics: Supports analysis of complete genomes, including comparative genomics across over 190 species.
• Proteomics: Facilitates proteome characterization and annotation using integrated resources such as UniProt and InterPro.
• Comparative and Evolutionary Analyses: Enables cross-species comparisons and inference of evolutionary relationships using statistical overviews.
• Functional Annotation and Target Identification: Aids functional interpretation of genes and proteins and identification of candidate targets for drug discovery.
• Microbial and Archaeal Genomics: Enhances bacterial and archaeal sequence annotation through integration with Genome Reviews and other databases.

Methodology:

Analyses are prepared using Genome Reviews to enhance bacterial and archaeal DNA sequence annotations by integrating data from EMBL Nucleotide Sequence Database, UniProt Knowledgebase, InterPro, CluSTr, GOA (Gene Ontology Annotation), and HOGENOM.