InterMine

InterMine integrates heterogeneous biological datasets into a unified data warehouse to enable complex cross-dataset queries and programmatic bioinformatic analyses.

Key Features:

• Data Integration: Uses an extensible data model to import and harmonize diverse biological data types and formats.
• Customizable Query Facility: Provides a fast, configurable query builder supporting genomic region searches and statistical analysis via widget-based components.
• Extensibility and Customization: Supports adding new tools and functionalities through an extensible architecture.
• Web Services and Programming Language Support: Automatically generates RESTful web services for data filtering, flexible export, list manipulation, sequence segment retrieval, and statistical analysis, with client libraries available in five programming languages.
• Data Export: Exports query results in multiple community-standard formats.

Scientific Applications:

• Integrative Analysis: Construction and querying of large-scale integrated biological databases combining multiple heterogeneous datasets.
• Comparative Genomics and Proteomics: Cross-dataset comparative analyses across genomic and proteomic data.
• Systems Biology: Integration of genomic, proteomic, and other molecular data to support systems-level investigations.
• Disease Mechanism Exploration: Detailed exploration of biological processes and disease mechanisms using flexible queries and statistical widgets.

Methodology:

Imports and harmonizes heterogeneous data sources and formats using an extensible data model and exposes programmatic access via automatically generated RESTful web services.