invertiaDB

invertiaDB compiles inverted repeats identified across 118 101 organisms spanning all major taxonomic groups, providing a centralized repository for searching, visualizing, and downloading inverted repeat sequences.

Key Features:

• Comprehensive Taxonomic Coverage: The database contains inverted repeats from 118 101 organisms across all major taxonomic groups in the tree of life.
• Inverted Repeat Identification Parameters: Repeats were identified with arm lengths of at least 10 bp, spacer lengths up to 8 bp, and no mismatches in the arms.
• Sequence Data Repository: The database hosts 34 330 450 inverted repeat sequences for access and download.
• Interactive Visualization: The database supports interactive visualizations of inverted repeat data.
• Search Functionality: Users can perform searches within the inverted repeat dataset.
• Data Download: Existing inverted repeat data can be downloaded for independent analysis.

Scientific Applications:

• Genomic Instability Research: Inverted repeats are linked to genomic instability, and the database enables study of these elements across diverse organisms.
• Comparative Genomics: The database facilitates comparison of inverted repeat distribution across taxonomic groups, which differ markedly in the tree of life.
• Polymorphism Studies: Inverted repeats exhibit high polymorphism due to their inherent genomic instability, and the database supports investigation of this variation.
• Structural Biology: Inverted repeats can form hairpin and cruciform structures, and the database enables analysis of these structural elements.
• Functional Genomics: Inverted repeats have various biological functions that can be investigated using the comprehensive dataset.

Methodology:

Inverted repeats were identified with arm lengths of at least 10 bp, spacer lengths up to 8 bp, and no mismatches in the arms.