iPath3.0

iPath3.0 integrates four KEGG global maps, up to 158 KEGG pathway maps and 192 KEGG modules into a single connected manually curated metabolic network to visualize and analyze cellular metabolism.

Key Features:

• Integrated metabolic network: Integrates four KEGG global maps, up to 158 KEGG pathway maps and 192 KEGG modules into a single connected network.
• Manual curation: Provides a manually curated representation of metabolic pathways and elements.
• Inclusion of metabolic elements: Incorporates KEGG modules and additional metabolic elements within the network.
• Multi-omics trend highlighting: Highlights general metabolic trends within multi-omics datasets.
• Multi-condition and time-series support: Supports visualization and analysis across multiple experimental conditions and time-series datasets.
• Customization data generation: Generates customization data for mapping experimental results onto the network.
• Programmatic access: Provides programmatic access for automated analysis and integration into computational workflows.
• Multi-level navigation: Enables navigation at various levels of detail to investigate identified trends.

Scientific Applications:

• Pathway visualization: Visualization and exploration of cellular metabolic pathways using integrated KEGG maps and modules.
• Multi-omics analysis: Identification and highlighting of metabolic trends within multi-omics datasets.
• Comparative and time-series analysis: Comparative analysis of metabolic changes across experimental conditions and time-series datasets.
• Network-based interpretation: Interpretation of metabolic networks reconstructed from KEGG pathway maps and KEGG modules.

Methodology:

Integration of four KEGG global maps with up to 158 KEGG pathway maps and 192 KEGG modules into a single connected manually curated metabolic network, generation of customization data, provision of programmatic access, and support for navigation at multiple levels of detail.