iRibo

iRibo integrates any number of ribosome profiling samples to obtain sensitive inference of annotated or unannotated translated open reading frames.

Key Features:

• Sample Integration: iRibo integrates any number of ribosome profiling samples for analysis.
• ORF Detection: iRibo infers both annotated and unannotated translated open reading frames.
• Translatome Generation: iRibo generates a species' translatome from a set of ribosome profiling samples.

Scientific Applications:

• Genome-wide Translation Detection: iRibo provides integrative detection of genome-wide translation across a genome.
• Yeast Translatome Analysis: iRibo has been demonstrated for generating a translatome using S. cerevisiae as an example.

Methodology:

iRibo uses ribosome profiling, a sequencing technique that provides a global picture of translation across a genome.