Interactive Tree Of Life (iTOL)

Interactive Tree Of Life (iTOL) visualizes and annotates phylogenetic trees and related tree structures to display evolutionary relationships and associated metadata.

Key Features:

• Versatile Display Options: Supports various tree layouts, including circular layouts, and scales to trees with up to 100,000 leaves.
• Comprehensive Annotation Capabilities: Annotates trees with diverse data types such as genome sizes and protein domain repertoires and supports numerous dataset types and expanded annotation options.
• Interactive Manipulation Tools: Provides interactive pruning and re-rooting of trees.
• Advanced Data Integration: Directly visualizes Qiime 2 trees and associated annotations and supports the phylogenetic placements format.
• Export Options: Exports trees in multiple graphical formats, including bitmap and vector formats.
• Batch Access Interface: Enables programmatic upload and export of trees and annotations for integration with other web services and workflow automation.

Scientific Applications:

• Evolutionary Biology: Visualizing complex phylogenetic relationships among organisms for evolutionary analyses.
• Comparative Genomics: Integrating genome sizes and protein domain repertoires for comparative analyses across organisms.
• High-throughput Phylogenetics and Microbiome Studies: Handling large trees and annotated datasets from workflows such as Qiime 2 and phylogenetic placements for large-scale studies.

Methodology:

Visualization of trees with multiple layouts (including circular), annotation with diverse dataset types, interactive pruning and re-rooting, direct visualization of Qiime 2 trees and the phylogenetic placements format, programmatic batch upload/export, and export to bitmap and vector graphical formats.