iview

iview displays interactive HTML5 WebGL-based 3D visualizations of protein-ligand complexes to support analysis of molecular interactions and structure-based drug design.

Key Features:

• Hardware Acceleration: Uses WebGL for hardware-accelerated rendering to enable high-performance visualization of molecular structures.
• Virtual Reality Support: Provides VR visualization modes including Anaglyph, Parallax Barrier, and Oculus Rift for stereoscopic exploration of complexes.
• Surface Representations: Supports Van der Waals Surface, Solvent Excluded Surface, Solvent Accessible Surface, and Molecular Surface representations for analyzing molecular surfaces.

Scientific Applications:

• Structure-based Drug Design: Facilitates evaluation of ligand binding modes and complementarity to inform rational drug design efforts.
• Protein-Ligand Docking Analysis: Assists interpretation and visual inspection of docking results for protein-ligand complexes.
• Intermolecular Interaction Analysis: Enables examination of intermolecular contacts and geometries to study molecular mechanisms in biology.

Methodology:

Implements hardware-accelerated rendering via WebGL within an HTML5 framework, offers VR modes (Anaglyph, Parallax Barrier, Oculus Rift), and renders Van der Waals, Solvent Excluded, Solvent Accessible, and Molecular surface representations.