iVirus

iVirus integrates CyVerse and KBase resources to analyze double-stranded DNA (dsDNA) viruses and support ecological analyses of viral impacts on microbial ecosystems.


Key Features:

  • Integrated Analytical Platforms: Core iVirus applications have been integrated into KBase to enable comprehensive analyses of dsDNA viruses across ecosystems.
  • Expanded Software Tools: At CyVerse, the iVirus suite includes upgrades to 20 existing apps and newly added capabilities for viral sequence analysis.
  • Enhanced Data Aggregation: The platform aggregates nearly 20-fold more sequence reads from diverse environments, increasing data breadth for viral ecology studies.

Scientific Applications:

  • Ecological impact assessment: Supports studies of how dsDNA viruses influence microbial community structure and ecosystem processes.
  • Cross-ecosystem viral surveys: Enables analysis of aggregated viral sequence data from diverse environments to compare viral community composition and abundance.
  • KBase-enabled analyses: Leverages KBase integration to provide additional analytical capabilities for tailored viral ecology investigations.

Methodology:

Aggregation and analysis of large-scale environmental sequence reads using an extensive suite of bioinformatics tools to analyze viral communities, assess ecological roles, and explore interactions with microbial hosts.

Topics

Details

Cost:
Free of charge
Tool Type:
web application
Operating Systems:
Mac, Linux, Windows
Added:
3/21/2023
Last Updated:
11/24/2024

Operations

Publications

Bolduc B, Zablocki O, Guo J, Zayed AA, Vik D, Dehal P, Wood-Charlson EM, Arkin A, Merchant N, Pett-Ridge J, Roux S, Vaughn M, Sullivan MB. iVirus 2.0: Cyberinfrastructure-supported tools and data to power DNA virus ecology. ISME Communications. 2021;1(1). doi:10.1038/s43705-021-00083-3. PMID:36765102. PMCID:PMC9723767.

PMID: 36765102
PMCID: PMC9723767
Funding: - NSF | BIO | Division of Biological Infrastructure: DBI-1743442 - DOE | Office of Science: DE-AC02-05CH11231, DE-AC52-07NA27344, SCW1632, SCW1656 - National Science Foundation: 1663578

Links