JCBIE

JCBIE performs joint continual learning to extract biomedical entities and relations from corpora for construction and expansion of large-scale Biomedical Knowledge Graphs (BKGs).


Key Features:

  • Joint Continual Learning Approach: Integrates joint learning and continual learning strategies to incrementally learn new entity types and relations while retaining previously acquired knowledge for BKG construction.
  • Dual Encoder Architecture: Employs two separate encoders rather than a single hard-parameter sharing encoder to mitigate feature confusion and provide distinct feature representations for entities and relations.
  • Entity-Augmented Inputs: Uses entity-augmented inputs to enable interaction between named entity recognition (NER) and relation extraction tasks, improving entity identification and relation linking.
  • Cross-Corpus Generalization Evaluation: Implements an evaluation mechanism that measures cross-corpus generalization errors to assess robustness across different corpora.

Scientific Applications:

  • Biomedical Knowledge Graph construction: Facilitates extraction of diverse biomedical entities and relations to build and expand large-scale BKGs.
  • Downstream biomedical research: Supports applications such as drug discovery, disease modeling, and personalized medicine by providing structured entity and relation data.

Methodology:

Empirically compares joint learning and continual learning strategies; implements a dual encoder architecture; employs entity-augmented inputs to enable NER–relation extraction interaction; and uses a cross-corpus generalization evaluation to measure generalization errors.

Topics

Details

License:
Not licensed
Cost:
Free of charge
Tool Type:
command-line tool
Operating Systems:
Mac, Linux, Windows
Programming Languages:
Python
Added:
2/23/2023
Last Updated:
2/23/2023

Operations

Publications

He K, Mao R, Gong T, Cambria E, Li C. JCBIE: a joint continual learning neural network for biomedical information extraction. BMC Bioinformatics. 2022;23(1). doi:10.1186/s12859-022-05096-w. PMID:36536280. PMCID:PMC9761970.

PMID: 36536280
PMCID: PMC9761970
Funding: - Key Research and Development Program of Shaanxi Province: 021GXLH-Z-095 - Innovative Research Group of the National Natural Science Foundation of China: 61721002 - Innovation Research Team of the Ministry of Education, Project of China Knowledge Centre for Engineering Science and Technology: IRT_17R86 - Key Research and Development Program of Ningxia Hui Nationality Autonomous Region: 2022BEG02025