kc-hits

kc-hits automates the evaluation and classification of chemical carcinogens to characterize their carcinogenic potential by integrating diverse data sources.


Key Features:

  • Automation: Automates evaluation steps to reduce manual intervention and potential human error.
  • Efficiency Improvements: Processes large datasets to improve throughput and consistency of results.
  • Comprehensive Analysis: Integrates diverse data types relevant to carcinogenic evaluation to consider key characteristics of potential carcinogens.

Scientific Applications:

  • Toxicological carcinogen assessment: Applied in toxicology to assess carcinogenic hazards of chemical substances and to inform regulatory and research decision-making.

Methodology:

Implements a systematic automated workflow that characterizes chemicals based on carcinogenic potential through integration of various data sources and automated analysis techniques.

Topics

Details

License:
MIT
Cost:
Free of charge
Tool Type:
workflow
Operating Systems:
Windows
Programming Languages:
Python
Added:
6/28/2022
Last Updated:
11/24/2024

Operations

Publications

Reisfeld B, de Conti A, El Ghissassi F, Benbrahim-Tallaa L, Gwinn W, Grosse Y, Schubauer-Berigan M. kc-hits: a tool to aid in the evaluation and classification of chemical carcinogens. Bioinformatics. 2022;38(10):2961-2962. doi:10.1093/bioinformatics/btac189. PMID:35561175. PMCID:PMC9306747.

PMID: 35561175
PMCID: PMC9306747
Funding: - National Institutes of Health and National Cancer Institute: NIH-NCI U01CA033193