KG-COVID-19

KG-COVID-19 constructs integrated knowledge graphs by downloading and transforming SARS-CoV-2 and COVID-19 datasets to support data integration and computational analyses.


Key Features:

  • Customization for diverse applications: Produces customized knowledge graphs for downstream analyses such as machine learning and hypothesis-based querying.
  • Integration of biomedical data: Ingests and integrates biomedical datasets related to SARS-CoV-2 and COVID-19 into a unified knowledge graph.
  • KG Hub design patterns: Leverages design patterns from the KG Hub to guide graph construction and data harmonization.
  • Data ingestion and transformation: Automates downloading and transformation of source datasets into a cohesive knowledge graph.
  • Multiple serialization formats: Outputs prebuilt graph versions in various serialization formats.
  • Adaptability to other biomedical problems: Applies the same framework to integrate non-COVID-19 biomedical datasets as needed.

Scientific Applications:

  • Machine learning and predictive modeling: Enables training and application of machine learning models on integrated SARS-CoV-2 and COVID-19 data for predictive analyses.
  • Hypothesis-driven exploration: Supports hypothesis-based querying to discover relationships within the integrated COVID-19 knowledge graph.
  • Cross-dataset discovery: Facilitates discovery of relationships across integrated COVID-19 datasets to inform research questions.

Methodology:

The framework downloads, ingests, transforms, and integrates SARS-CoV-2/COVID-19 datasets following KG Hub design patterns and outputs prebuilt knowledge graphs in various serialization formats.

Topics

Collections

Details

Tool Type:
command-line tool
Added:
1/18/2021
Last Updated:
2/12/2021

Operations

Publications

Reese J, Unni D, Callahan TJ, Cappelletti L, Ravanmehr V, Carbon S, Fontana T, Blau H, Matentzoglu N, Harris NL, Munoz-Torres MC, Robinson PN, Joachimiak MP, Mungall CJ. KG-COVID-19: a framework to produce customized knowledge graphs for COVID-19 response. Unknown Journal. 2020. doi:10.1101/2020.08.17.254839. PMID:32839776. PMCID:PMC7444288.