kinfitr

kinfitr performs kinetic modelling of Positron Emission Tomography (PET) data to quantify tracer pharmacokinetics and support reproducible PET analyses.

Key Features:

• Model selection: Supports 14 different kinetic models for PET pharmacokinetic analysis.
• Goodness-of-fit assessment: Includes tools to assess goodness of fit for each applied model.
• PET data handling: Provides routines for managing and preprocessing PET data prior to modelling.
• Reproducibility and transparency: Encourages sharing of analysis code and data to enable independent verification of results.
• R implementation: Implements models and analysis routines within the R programming language.

Scientific Applications:

• Neurology: Quantification of tracer kinetics to study neurological processes and targets.
• Oncology: Measurement of tracer uptake and kinetics in tumor imaging studies.
• Cardiology: Assessment of cardiac tracer kinetics for studies of myocardial physiology and pathology.

Methodology:

Implements kinetic modelling of PET data using 14 specified models, provides goodness-of-fit assessment tools and PET data handling routines within R, and supports sharing of analysis code for reproducible workflows.