krisp

krisp classifies Dengue, Chikungunya, and Zika viral sequences by species, serotype, and genotype to monitor virus genotype diversity.

Key Features:

• Efficient classification methodology: Employs a novel algorithm to classify viral sequences at species and sub-species levels, including serotype and genotype distinctions.
• Comprehensive validation: Validated on large datasets encompassing whole-genome and partial-genome sequences to assess classification performance across complete and partial genomic data.

Scientific Applications:

• Epidemiological surveillance: Provides genotype-level classification to support epidemiological studies and public health strategies for Dengue, Chikungunya, and Zika.
• Evolutionary and dissemination tracking: Enables tracking of virus evolution and dissemination patterns to inform targeted prevention and treatment strategies.

Methodology:

Uses an algorithm that distinguishes species and sub-species (including serotype and genotype) from genetic sequence data and has been validated on whole-genome and partial-genome datasets.