Krona

Krona visualizes hierarchical taxonomic and functional abundances in metagenomic datasets, representing relative proportions and prediction confidence levels.

Key Features:

• Hierarchical Visualization: Displays complex taxonomic and functional hierarchies while preserving quantitative relationships across levels.
• Radial Space-Filling Displays: Encodes hierarchical structure and abundance using a variant of radial space-filling visualization.
• Parametric Coloring and Polar-Coordinate Zooming: Applies parametric coloring and polar-coordinate zooming to emphasize values and enable focused exploration of hierarchical regions.
• Representation of Confidence: Represents prediction confidence levels alongside relative abundances within the hierarchy.
• Interactive HTML5/JavaScript Charts: Generates interactive visualizations implemented with HTML5 and JavaScript.

Scientific Applications:

• Metagenomic community profiling: Visualizes the abundance and distribution of taxa and functional groups in metagenomic studies.
• Interpretation of classification and annotation outputs: Aids interpretation of taxonomic and functional assignment results by combining hierarchical context with abundance and confidence information.
• Integration with analysis workflows: Serves as a visualization layer for outputs from metagenomic classification and functional annotation tools.

Methodology:

Implements a radial space-filling display variant with parametric coloring and polar-coordinate zooming to represent hierarchical quantitative relationships and confidence, and exports interactive HTML5/JavaScript charts.